Fluoride Toxicity

Melatonin Protection on Mercury Exerted Brain Toxicity in the Rat. Mandava V. Rao, Anshita Purohit Zoology Department, University School of Sciences, Gujarat University, Ahmedabad 380 009, India. Website: www.zoologygujaratuni.org Abstract: Effect of melatonin on the neuro noxiousity plant on by mercuric chloride was studied. Adult rats were fed by word of mouth with ii different doses of mercuric chloride (2mg; 4mg/kg body weight) to survey thought toxicity with respect to cerebral cerebral hemisphere, cerebellum, bulb oblongata regions for 60 eld with and without supplementation of melatonin (5mg/kg body weight) intraperitoneally. The results intimate that the graded doses of mercury elicit the depletion of the enzymatic activities like adenosine triphosphatase, succinate dehydrogenase, phosphorylase, alkalic phosphatase, acid phosphatase, and neutered glycogen, protein and lipid peroxidation levels in creative nous of cerebral hemisphere, cerebellum and med ulla oblongata of brain affecting their respective functions. race glucose and mercury levels increased followed by a reduction in body and organ weights. on the whole these effects seemed to be severe in cerebral hemisphere of brain.

Further affect indices were to some extent maintained in the brain of animals co-treated with melatonin show it protective role against mercury exerted neurotoxicity in the rat brain. submission: Mercury is a serious environmental and occupational pollutant with toxic effects in all the liveliness organisms (Berlin, 1987). Primary exposures results out-of-pocket to environmenta l contamination caused as a result of mining! , smelting, extensive industrial and agricultural usage including stirring and ingestion via the viands chain. It enters in the body in contour of chemical forms that be elemental, inorganic and organic, exhibiting its toxicology characters including neurotoxicity, nephrotoxicity, reproductive toxicity and GI toxicity with ulceration and hemorrhage (Clausen, 1993; Hua et...If you want to observe a replete(p) essay, order it on our website: BestEssayCheap.com

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